1-[2-(trifluoromethyl)phenyl]ethan-1-amine

1-[2-(trifluoromethyl)phenyl]ethan-1-amine - Names and Identifiers

Name	Benzenemethanamine, a-methyl-2-(trifluoromethyl)-
Synonyms	1-(2-Trifluoromethylphenyl)ethylamine 1-(2-(Trifluoromethyl)phenyl)ethylamine (1-[2-(Trifluoromethyl)phenyl]ethylamine 1-[2-(trifluoromethyl)phenyl]ethan-1-amine (RS)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE Benzenemethanamine, α-methyl-2-(trifluoromethyl)- Benzenemethanamine, a-methyl-2-(trifluoromethyl)- 1-[2-(Trifluoromethyl)phenyl]ethylamine, 2-(1-Aminoethyl)benzotrifluoride
CAS	273384-78-4

1-[2-(trifluoromethyl)phenyl]ethan-1-amine - Physico-chemical Properties

Molecular Formula	C9H10F3N
Molar Mass	189.18
Density	1.18 g/cm³
Boling Point	68.7-71.1
Flash Point	78.8 °C
Water Solubility	at 25 deg C (mg/L): 4087
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

1-[2-(trifluoromethyl)phenyl]ethan-1-amine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R34 - Causes burns R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	2735
Hazard Note	Irritant

1-[2-(trifluoromethyl)phenyl]ethan-1-amine - Introduction

Benzenemethanamine, a-methyl-2-(trifluoromethyl)-is an organic compound with the chemical formula C9H10F3N. It is a colorless liquid with a benzene fragrance. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless liquid
-Molecular weight: 189.18g/mol
-Melting point:-46 ℃
-Boiling point: 197-199 ℃
-Flash Point: 77 ℃
-Density: 1.199 g/mL
-Solubility: Soluble in common organic solvents, such as alcohol, ether, ketone, etc

Use:
- Benzenemethanamine, a-methyl-2-(trifluoromethyl)-is mainly used as a reagent in organic synthesis. It can be used as an antagonistic agent for hydrofluoric acid, protonating reagents and acid-catalyzed reactions. At the same time, it can also be used to synthesize new drugs and pesticides.

Method:
-Benzenemethanamine, a-methyl-2-(trifluoromethyl)-can be prepared by the following steps-:
1. Benzyl bromide reacts with dimethylformamide in an ice bath to generate formyl benzylamine.
2. The formylbenzylamine reacts with trifluoromethyl borate under alkaline conditions to generate Benzenemethanamine, a-methyl-2-(trifluoromethyl)-.

Safety Information:
- Benzenemethanamine, a-methyl-2-(trifluoromethyl)-The following safety precautions should be paid attention to during operation and storage:
-It is an irritating compound, avoid contact with skin and eyes. Wear appropriate personal protective equipment such as gloves, goggles or face shield when using.
-Avoid inhaling gases or vapors from solutions, ensure well-ventilated workplaces or wear respiratory protective equipment.
-Avoid contact with oxidants and strong acids to prevent dangerous reactions.
-Follow correct operating procedures during use, and store and handle the compound properly. In case of accidental leakage or splashing, take appropriate emergency measures immediately and seek medical help.

Last Update：2024-04-09 19:05:48